Structure of PDB 8q3x Chain DDD Binding Site BS01

Receptor Information
>8q3x Chain DDD (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>8q3x Chain III (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagatactaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctgaatcagctgaacatgccttttgatggagc
agtttccaaatacacttttggtagtatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB8q3x Viral peptide conjugates for metal-warhead delivery to chromatin.
Resolution2.301 Å
Binding residue
(original residue number in PDB)
S29 S52 R83 S84 T85
Binding residue
(residue number reindexed from 1)
S2 S25 R56 S57 T58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8q3x, PDBe:8q3x, PDBj:8q3x
PDBsum8q3x
PubMed38495982
UniProtO60814|H2B1K_HUMAN Histone H2B type 1-K (Gene Name=H2BC12)

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