Structure of PDB 7pub Chain DD Binding Site BS01

Receptor Information
>7pub Chain DD (length=790) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSGKARAFVFRDPSLRMMRAGSGYQQLRRMGMPMQVGMGWRKVDSFHANT
QYQHAWPLLSHDDLGNSDQSNNTKNIMYSMYMPKRNKGTAPWFRGADTYS
VKYCEQGRYEYQRYLMINRFPSEYKKHFLSFLSNIRMSSGSATIPQEALH
WLLRMIVDNFNPQHVHYIAAMKTLQSAGELDMARDVWKIMERQQTWPCTA
TICAYLDVCVEAGEKTWAMEAWNRYCTELKFLEPGEVDPKPISRVPFSLT
REELLYLPKWKKHFDHDPNLDVMDLNRFNRTREVYLRMAQVMLAGGERNA
FQHFFTKLEEAMLNKPTPVPEPPNPHLVRRPRWAPYEHCKSVHHSPWRLQ
NNGRALALGPPVTIEDEMQSRFFSNDQFLVHSVKEVLRIVLQEHKRAHPT
ECTRCKTEAFFYKTKDADETLKFCDDLIERLFASLGVRLSNLNTSSLLST
ILEVFRVVGKESGAALLQRANEFLERKASLGDAEGSRENLTASNYLQVLS
GFADESAFVYNTKKDGTCQYKTGFDPRTTMRHLADVVQEIAGNPHVTWAA
DMHLQVVETMVGCGTMKANDYFVRNVLRQFSWDSRFLEALYVEYRRQDDV
DMWAELTKRALVWTARYNAPASERLRRLIEDDYDTIRVQTRTFRELAVFQ
FRDVEERRHSRDVVNELPNPWYDYVAHALPFPDRDAGYPDEYGDLGQWRA
PGGPGSPVRGPRGYTAEWRDLRNPMRPPEFPTPWERKYRQYARGQHPSYD
MVYAGPMPEIFPMRRDFRKPTRWDFHDIEKQGKYRTSGPY
Ligand information
>7pub Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaagugcug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
aaaaauauauuuuuuuuuuuu
....................<<<.......<<<<<<............<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
..................................................
.................<<<.....<<<<<.....<<....>>.......
>>>>>>>>....>>.>>>>...............................
..................................................
..............................>>>....<............
.<<<<<............................................
..................................................
.....................>>>>>..................>.....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7pub Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
R11 S12 K14 A15 R16 A17 R21 P23 R26 A30 R38 M44 Q45 V46 G47 W50 R51 K52 F56 G75 R95 K97 D107 T108 Y109 K136 S143 S149 S151 A152 R339 R342 Q707 W708 A710 Y763 D772 K805
Binding residue
(residue number reindexed from 1)
R1 S2 K4 A5 R6 A7 R11 P13 R16 A20 R28 M34 Q35 V36 G37 W40 R41 K42 F46 G65 R85 K87 D97 T98 Y99 K126 S133 S139 S141 A142 R329 R332 Q697 W698 A700 Y741 D750 K783
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000963 mitochondrial RNA processing
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0031019 mitochondrial mRNA editing complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7pub, PDBe:7pub, PDBj:7pub
PDBsum7pub
PubMed35042777
UniProtQ385L8

[Back to BioLiP]