Structure of PDB 4v7l Chain DD Binding Site BS01 |
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| >4v7l Chain DA (length=2800)
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agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga
cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc
uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc
uugcgcggggggaaccuggggaacugaaacaucucaguacccagaggaga
ggaaagagaaaucgacucccugaguagcggcgagcgaaaggggaccagcc
uaaaccguccggcuuguccgggcggggucgggggcccucggccgaauccc
cagccuagccgaagcuguugggaagcagcgccagagagggugaaagcccc
guaggcgaaagguggggggauaggugaggguacccgaguaccccgugguu
cguggagccaugggggaaucugggcggaccaccgccuaaggcuaaguacu
ccgggugaccgauagcgcaccaguaccgugagggaaaggugaaaagaacc
ccgggaggggagugaaauagagccugaaaccgugggcuuacaagcaguca
cggccccaagggguuguggcgugccuauugaagcaugagccggcgacuca
cggucgugggcgagcuuaagccguugaggcggaggcguagggaaaccgag
uccgaacagggcgguccgcggccguggacccgaaaccgggcgagcuagcc
cuggccagggugaagcuggggugagacccaguggaggcccgaaccggugg
gggaugcaaaccccucggaugagcuggggcuaggagugaaaagcuaaccg
agcccggagauagcugguucuccccgaaaugacuuuagggucagccucag
gcgcugacuggggccuguagagcacugauagggcuagggggcccaccagc
cuaccaaacccugucaaacuccgaagggucccagguggagccugggagug
agggcgcgagcgauaacguccgcguccgagcgcgggaacaaccgagaccg
ccagcuaaggcccccaagucugggcuaagugguaaaggauguggcgccgc
gaagacagccagucgaguggcgccgcgccgaaaaugaucggggcuuaagc
ccagcgccgaagcugcgggucugggggaugaccccaggcgguaggggagc
guucccgaugccgaugaaggccgacccgcgagggcggcuggagguaaggg
aagugcgaaugccggcaugaguaacgauaaagagggugagaaucccucuc
gccguaagcccaaggguuccuacgcaauggucgucagcguaggguuaggc
gggaccuaaggugaagccgaaaggcguagccgaagggcagccgguuaaua
uuccggcccuucccgcaggugcgauggggggacgcucuaggcuaggggga
ccggagccauggacgagcccggccagaagcgcagggugggagguaggcaa
auccgccucccaacaagcucugcgugguggggaaaaccccccgaagccag
ggagccaagaaaagccucuaagcacaaccugcgggaacccguaccgcaaa
ccgacacaggugggcgggugcaagagcacucaggcgcgcgggagaacccu
cgccaaggaacucugcaaguuggccccguaacuucgggagaaggggugcu
cccuggggugaugagccccggggagccgcagugaacaggcucuggcgacu
guuuaccaaaaacacagcucucugcgaacucguaagaggagguauaggga
gcgacgcuugcccggugccggaaggucaaggggaggggugcaagccccga
accgaagccccggugaacggcggccguaacuauaacgguccuaagguagc
gaaauuccuugucggguaaguuccgaccugcacgaaaagcguaacgaccg
gagcgcugucucggcgagggacccggugaaauugaacuggccgugaagau
gcggccuacccguggcaggacgaaaagaccccguggagcuuuacugcagc
cugguguuggcucuuggucgcgccugcguaggauaggugggagccuguga
acccccgccuccgggugggggggaggcgccggugaaauaccacccuggcg
cggcugggggccuaacccucggauggggggacagcgcuuggcgggcaguu
ugacuggggcggucgccuccuaaaagguaacggaggcgcccaaagguccc
cucaggcgggacggaaauccgccggagagcgcaaggguagaagggggccu
gacugcgaggccugcaagccgagcaggggcgaaagccgggccuagugaac
cgguggucccguguggaagggccaucgaucaacggauaaaaguuaccccg
gggauaacaggcugaucucccccgagcguccacagcggcggggagguuug
gcaccucgaugucggcucgucgcauccuggggcugaagaaggucccaagg
guugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacguc
gugagacaguucggucucuauccgccacgggcgcaggaggcuugaggggg
gcucuuccuaguacgagaggaccggaagggacgcaccucugguuucccag
cugucccuccaggggcauaagcuggguagccaugugcggaagggauaacc
gcugaaagcaucuaagcgggaagcccgccccaagaugaggccucccacgg
cgucaagccgguaaggacccgggaagaccacccgguggaugggccggggg
uguaagcgccgcgaggcguugagccgaccggucccaaucguccgaggucu |
<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<<
<<<.[...((.>>>.....<<<<<<<..<<<))...].>>>.....>>>>
>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<<
..>>>>>>.>>....<<<<<.....<......>......>>>>>......
.....<<....>>...<<<<<.....<<.....>>....>>>>>...<<<
....<<<<<<<<.....>>>>>>>>.....<<<<<<<<...<<...<<<<
..<<<<.<<<...<<<<<......>>>>>((......<<<.....))>>>
...>>>...>>>>...>>>>..>>..>>>>>.>>>.....<<<<<<<<<.
......>>>>>>>>>......<<<<<..((((>>>>>..>>>......>>
.>>>>>>.>>...............<<....>>....>>.........<<
<<....>>>>..................>>>>>>>>>>>.......<<<<
<<<<<<<..>>>>>>>>>>>...<............>.<<<<<<....<<
<<<<<<<<<<...<<<...<<<.....>>>...>>>...<<....>>..<
<<<.....>>>>..>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<
<<<<<..<<<....<<<<<<......>>>>>>.....>>>...<<<<.<<
<<........>>>>>>>>....>>>>>>>>>...<<<.....>>>.....
.>>>>>>.......>>>..<<<<<<....<<<<<....>>>>><<<<<<<
<<.....<<<<<<<<<...<<<...<<<.<<<<...<<<<<........>
>>.>>...>>>>.>>>..>>.>...>>>>>>>>>.....>>>>>>>.>>.
.<<<<<<<.<<......>>.>>>>>>>.....<<<......>>>...<<<
<.<<<...<<<(((.....<<<<<<...........<<..<<<<<<<<<.
.................>>>>>>>>>.>>..........)))......>>
>>>>.>>>...>>>>>>>.<<<<<<.......>>>>>>.....>>>>>><
.<<<<<...<<<......<<<<<.<<<....>>>>>>>>...>>>..>>>
>>..>.....>>>>>><......<<.....<<<<<<.......>>>>>><
<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<
<<<.<<...<<<...<<<....>>>...>>>...>>...<<<<<......
..>>>>>))<<<<<<<<<<<<<...<<<<....<<<<<.<<<..<<<<<.
<<<<.<<..[[[....>>>>>><<<...<<<<<<<<<<<<<<<<.<<...
..>>>>>>>>>.....>>>>>>>>>..>>><.....>>>>>>...>>>..
>>>>>.........>>>.>..>>...>>>>>>>>>>>>>>>..>>.....
<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<
<<<<.<<.........<.....<<<<<.....<..>......>>>>><<<
<<<<<<<<<.....>>>>>>>>>>>>............<<<<<<<<<..<
<<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>
>>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<....>>>>>..
.>>...>>>>>>>>..>>>>><<<<<<.......>>>>>>........<.
..........<<<<<.......>>>>>.....>....>>>>>..>>.>>>
>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<.......
.>>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<
<.<<<<<.<<<<<<<<<<<<<<<<...........<<<<<..<<<.....
.<<<<<<<<....>>>>>>>>...>>>............>>>>>..>>>>
>>>>>>>>>>>>...<<<<<....>>>>>....>>>>>.>>>..>>>>>.
.<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<
<...<<<<<<.......>>>>>>.....<....(((.>....>>>>>>>.
..<<<<..<<<......>>>..>>>>.<<<....>>>.>>))).......
<<<<<<<.<<..))))..>>>>>>>>>.............>>>>..>>>>
>>.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>
>>.>.......<<<<<.<.<<<<..<<<<<<<<<......>>>>>>>..>
>.<<<<<.....>>>>>.....>>>>...>...>>>.>>....<<<<<<<
....>>>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<.
.<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<
<<<<<<<.]]]>>>>>>...>>>>>...>>>>.>>>>>...<<<....<<
<<.............>>>>....>>>.>>>>.......>>>>>>>...<<
.......>>.....<<<<<<<<<.......>>>>>....<<<<<<<<.<<
<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>> |
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| PDB | 4v7l The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | K7 P8 Y9 T10 S12 R13 R14 F15 V18 F21 I24 E28 L37 K38 R43 N45 Q46 G47 R48 I49 T50 R52 R54 G55 G56 H58 K59 R60 L61 Y62 R63 K78 Y84 P86 R88 D99 E101 K102 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 T161 Y172 L177 P178 S179 E181 R183 A199 H201 K202 V205 L206 G207 K208 A209 G210 R211 S212 W214 R218 P219 H220 R222 G223 M226 N227 P228 V229 D230 H233 G235 G236 E237 G238 R239 A240 P241 R242 R244 S248 P249 W250 W252 Q253 T254 K255 G256 L257 K258 T259 R260 K261 R263 K264 P265 S266 F269 |
Binding residue
(residue number reindexed from 1) | K6 P7 Y8 T9 S11 R12 R13 F14 V17 F20 I23 E27 L36 K37 R42 N44 Q45 G46 R47 I48 T49 R51 R53 G54 G55 H57 K58 R59 L60 Y61 R62 K77 Y83 P85 R87 D98 E100 K101 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 T160 Y171 L176 P177 S178 E180 R182 A198 H200 K201 V204 L205 G206 K207 A208 G209 R210 S211 W213 R217 P218 H219 R221 G222 M225 N226 P227 V228 D229 H232 G234 G235 E236 G237 R238 A239 P240 R241 R243 S247 P248 W249 W251 Q252 T253 K254 G255 L256 K257 T258 R259 K260 R262 K263 P264 S265 F268 |
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| Enzyme Commision number |
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