Structure of PDB 6hiw Chain DB Binding Site BS01

Receptor Information
>6hiw Chain DB (length=1111) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DWASHMQRELFGEVDPLGGQAHKDYYRDVTRGYSPQYAPRNFANGGAVAY
PHIQSPYEYEEAAHRRVWLDHDVDRMREEFTQHRASLRSLASAQEREELL
RSRAAEYQVANTVHESESVHPIQQLYNSGGTSRSALKQQAVADRYSIAEQ
HSPLPLTTGVDRDALDEAQRTKDRILNDSFTAENLLITHGLREKEKHDFT
ILQRTVRIPFQGYDMDRFLAQQKGTPYGAQQLPPNVVPSSMEEAQRTLRG
SSATATPLVDAVAQKVYARNTVVDRPAIGEQLTEQIINIMRASRTTAEQQ
REEERAQRFGLGRQGALVQDGGPDQRTLKKHTNDERIVDAMLFQQNAYRK
TPTDEHWNPYIRRSTENGVGHLLQNKFDIMRREDRLSKGEQDLTERNTIH
YGVPIQQIVDEFVFRHRNARGERPLDYFKPFPNFRALRLNRMYRDVEGFS
LMKQRPEFLEWELFTRYRQHHQQRRRLALLHGLEPVANETAQERDTRRHR
LDEICERTPFDEREMRVNDDEMRVSVETLRSWFGVYMLPSPTVVNAVLGG
SASVNLHLYHLADEMGTADTREHVLSSRYLNRLLLLESYQNRVGRGFMNH
VVGRAPEPVVPHEQPQEVLRHFSAEERAMYEQHVKEQTSRQLGEWERAMK
RRRWLTDHQQYGHVVSHGLETSVVDLSHTETGAVLTVSTKAYEQEIEAVR
MKTNATIKVDGMVYNLLPNSERRVVPLTVQLDSGEKIDMTSEDFDRCELE
AFPRNLNHALNYGIANYAYNRGNYVETQDSIWEEQTASGQEGWSPATHAD
GLREGLPVRARRPIFSSSAEQRIAGGPQRAVIIQYHHQPFFNPEPRLVKV
AFQCDGTIMEVPISDVMIWQRRYHGPERTVGDESRRYNPAAMRRYVDVTD
PFNEKTSNTEHFLDKYEPKRNADTVADKYRTTKQITEIDKWTRYDSARAD
NYRPLSISHRRDYIRMGYIPRYTPWEWIAIQEADQPLIAEQIRQDNIGTS
YFFSLNRYWRYKASPHGYIRHFENEVRDLLQYVDGVTPWKQAQKIRTYWE
VRSHHPMPQFNRPEVAMHRNTVGLLPAHMWETDKKTGKVKSVKDSVRDYQ
TKTPYPKWVQL
Ligand information
>6hiw Chain UP (length=7) Species: 5702 (Trypanosoma brucei brucei) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PPPPPPP
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution3.37 Å
Binding residue
(original residue number in PDB)		V754 L755 T756 S758
Binding residue
(residue number reindexed from 1)		V684 L685 T686 S688
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0097014 ciliary plasm

View graph for
Cellular Component
External links
PDB RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum6hiw
PubMed30213880
UniProtQ586P5

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