Structure of PDB 7qep Chain D6 Binding Site BS01

Receptor Information

>7qep Chain D6 (length=101) Species: 284813 (Encephalitozoon cuniculi GB-M1)

MRRNHGRGKKNRGSAGSIQCDKCGSVTPKDKAIKRFRIQSLIEQASFDDL
KQATIYDVFEVPRMGYKSQFCVSCACHAKIVRVRSSQARKIRYGFNPNRV
A

Ligand information

>7qep Chain 3 (length=1295)

aucagguugauucugccugacguggaugcuauucucuggggcuaagccau
gcaugcuugugaacucuuugugggggauuagcggacggcucagugauagc
acgaugauuuguuugcgggaugagcaguagcugcgggaaacugcagauag
uggucugccccuguggggguuggcaaguaaguugugggccuaucagcugg
uaguuaggguaauggccuaacuaggcgcagacgggauacgggggaucagg
guuugguuccggagagggagccugagagauggcuacuacguccaaggaug
gcagcaggcgcgaaacuugccuaauccuuuggggaggcgguuaugagaag
ugaugugugugcgagugcaaaggggucgcaugugauuggagggcaagucg
ggugccagcagccgcgguaauaccugcuccaauagugucuaugguggaug
cugcaguuaaaauguccguagucuguguaugucuuugugugugauguuug
ugguuguguguggauguagugaguguguggcagaggacgaggggcacugg
auaguugggcgagaggugaaaugcgaagacccugacuggacgagcggaag
cgaaggcugugcucuuggacuaauguugcgaugaaggacgaaggcuagag
gaucgaaaucgauuagauaccguuuuaguucuagcaguaaacgaugccga
cuggacgggacaguguguguuguccaugagaaaucuugaguaugcggguu
cuggggauaguaugcucgcaagagugaaacuugaagagauugacggaagg
acaccacaaggaguggagugugcggcuuaauuugacucaacgcggggcaa
cuuaccggcucugaaggaugccugugagugcauggcaugaggcaugcggc
gguggugcauggccguuuuaaauggauggcgugagcuuugucuuaaguug
cguaagaugugagacccuuugacgguguucuacggagcaaggaggggaug
gaagagaacagguccguuaugcccugagaugaggcgggcugcacgcgcac
uacgauagauggcgcuucugccugcugugagggaugaagcuguguaaggg
gcuucugaacguggaauuccuaguaauagcggcugacgaagcugcuuuga
augugucccuguccuuuguacacaccgcccgucgcuaucuaagaugacgc
acuggacgaagaucggaaggucugaguccugaguguuagauaagauauaa
gucguaacauggcugcuguuggagaaccagcagcaggaucaguau

..<<<<..[.((((.>>>>.<<<<<<<<<..<<<<<.<.......<<<.<
<<..<<<......<<<.....>>>.....>>>......<<.........<
<<<<<..<<..<<<<<.....<<.<<...<<<<<<......>>>>>.>..
>>.>>.<<<<<....>>>>>..>>>>>.>>>>>>>>..<<<....<<<..
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<<<<<<....
>>>>...>>>>.>>.<<.<<<..........>>>.>>.<<<<....>>>>
...>>>>>>.........<<<....<<....>>..>>>...>..>>>>>.
........<<<<<<.<.......>.>>>>>>....<<<<<((......<<
<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>.......
...<<<((.....<<<<...<<<....<<<<<<<....<<<<<<<.....
..>>>>>>>..>>>>>>>...........<<<.<<..<<.<<<<<<<<.<
.<<<<<<<<...<..........>......>>>>>>>>..>>.......<
<....>>.>>>>>>>>>..>>..>>>...>>>...>>>>....<<<<<<<
...<..<<.<<.<.....>.>>.>>..>>>>>>>>..........<<<.<
<.<<<<<<.<<<...>>>.>>>>>>..<<..))>>....>>.....>>>.
>>>.<<.......<<<<....>>>>.....>>..)))).]<<<<<.<<<<
<<<..<<.<<<<<<..<<<<<<<<<<......<<........>>......
....<<<.<<<......<<<<<.....<<<.....>>>..>>>>>....<
<<.<<<..<<.<<<<<<....<<<...<<<....>>>..<<........>
>......>>>.....<<........<<<<<....>>>>>..........>
>.....>>>.>>>.....>>>>>>>>....>>>.>>>...>>.>>>>>>>
>.....<<..<<<......>>>..>>....<....<<<<<<........>
>>>>>....>.....>>>>>>....<.<<<<<<.......>>>>>>.>..
....>>...>>>>>>>>>>.>>....<..<<.<..<<<<<.<...<<<<<
.<.<<<<..<<<<<....>>>>>..>>>>.>.>>>>>...>.>>>>>...
>.>>...>.....<<<<<<<<<....>>>>>>>>>..........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7qep Adaptation to genome decay in the structure of the smallest eukaryotic ribosome
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): M1 R2 R3 N4 H5 G6 N11 R12 G13 S14 K29 K31 R35 F36 K67 V72 C76 V81 R84 S85 R89 R92 Y93 G94 F95 R99
• Binding residue (residue number reindexed from 1): M1 R2 R3 N4 H5 G6 N11 R12 G13 S14 K29 K31 R35 F36 K67 V72 C76 V81 R84 S85 R89 R92 Y93 G94 F95 R99

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qep, PDBe:7qep, PDBj:7qep
• PDBsum: 7qep
• UniProt: Q8SRN2|RS26_ENCCU Small ribosomal subunit protein eS26 (Gene Name=RPS26)