Structure of PDB 8iyj Chain D3 Binding Site BS01

Receptor Information
>8iyj Chain D3 (length=424) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKEYEVACNTGAYTSSGLATAGFRTAKYLRDEWFQNSYARYHQAFADRDY
SERQRHESGQLVAETGALAQRTQLDSTRKVGERLEDMHCWKSELQREIDE
LSSETDLMMAQKLRLQRALDATSVPYSIATDNLQCRERRQHPDLVRDYVE
VELLKETELIRNIQELLKRTIGQAVDQIRLNREHKESCEMNWSDKVEVYN
IDDTCSRYTNESTQVQFYPHSSKFEESASTPETWAKFNHDNLLRAERERL
ASVNLRKLIDCILRDTAEDLRLQCDAVNSAFSSRCQELDDSLQKLQYHLR
KTLTEITDQEHQIAALKQAIKDKEAPLRVAQTRLYQRSHRPNVELCRDNA
QFRLLSEVEELNMSLRALKEKLQDAEQALRNLEDSRMSLEKDIAVKTNSL
FIDRQKCMTHRNRYPSVLQLAGYQ
Ligand information
>8iyj Chain X2 (length=24) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PYQGYESPCSGRHYCLRGMDYCTT
Receptor-Ligand Complex Structure
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PDB8iyj Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		L189 R192 Q196 L278 L281 C284 I285 D288 D292
Binding residue
(residue number reindexed from 1)		L166 R169 Q173 L255 L258 C261 I262 D265 D269
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
Biological Process
GO:0030030 cell projection organization
GO:0030317 flagellated sperm motility
GO:0060294 cilium movement involved in cell motility
GO:0060378 regulation of brood size
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005879 axonemal microtubule
GO:0031514 motile cilium
GO:0036126 sperm flagellum
GO:0097225 sperm midpiece
GO:0097228 sperm principal piece
GO:0160111 axonemal A tubule inner sheath

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8iyj, PDBe:8iyj, PDBj:8iyj
PDBsum8iyj
PubMed37295417
UniProtQ149S1|TEKT4_MOUSE Tektin-4 (Gene Name=Tekt4)

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