Structure of PDB 4w2f Chain D1 Binding Site BS01

Receptor Information
>4w2f Chain D1 (length=97) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRV
RVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL
Ligand information
>4w2f Chain CY (length=73) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccggauagcucagggagagcaggggauugaaaauccccguguccuugg
uucgauuccgaguccgggcacca
<<<<<<<..<<<<.....>>>>.<<<<<<.....>>>>>>.....<<<<<
.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB4w2f Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
K23 V30
Binding residue
(residue number reindexed from 1)
K22 V29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:4w2f, PDBe:4w2f, PDBj:4w2f
PDBsum4w2f
PubMed25306919
UniProtP60494|RL28_THET8 Large ribosomal subunit protein bL28 (Gene Name=rpmB)

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