Structure of PDB 8txn Chain D Binding Site BS01

Receptor Information
>8txn Chain D (length=676) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSPGS
CVPRFSTLPVLSCGQNNVCNYASRNDKTFWLTTNAAIPMMPVENIEIRQY
ISRCVVCEAPANVIAVHSQTIEVPDCPNGWEGLWIGYSFLMHTAVGNGGG
GQALQSPGSCLEDFRATPFIECNGAKGTCHFYETMTSFWMYNLESSQPFE
RPQQQTIKAGERQSHVSRCQVCMKNSRGFIFARHSQSVHVPQCPANTNLL
WEGYSLSGNVAASRAVGQDLGQSGSCMMRFTTMPYMLCDITNVCHFAQNN
DDSLWLSTAEPMPMTMTPIQGRDLMKYISRCVVCETTTRIIALHSQSMSI
PDCPGGWEEMWTGYSYFMSTLDNVGGVGQNLVSPGSCLEEFRAQPVIECH
GHGRCNYYDALASFWLTVIEEQDQFVQPRQQTLKADFTSKISRCTVCRRR
YLTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSPG
SCVPRFSTLPVLSCGQNNVCNYASRNDKTFWLTTNAAIPMMPVENIEIRQ
YISRCVVCEAPANVIAVHSQTIEVPDCPNGWEGLWIGYSFLMHTAVGNGG
GGQALQSPGSCLEDFRATPFIECNGAKGTCHFYETMTSFWMYNLESSQPF
ERPQQQTIKAGERQSHVSRCQVCMKN
Ligand information
Ligand IDCL
InChIInChI=1S/ClH/h1H/p-1
InChIKeyVEXZGXHMUGYJMC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cl-]
FormulaCl
NameCHLORIDE ION
ChEMBL
DrugBankDB14547
ZINC
PDB chain8txn Chain D Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8txn Collagen IV of basement membranes: IV. Adaptive mechanism of collagen IV scaffold assembly in Drosophila.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		A2074 R2076
Binding residue
(residue number reindexed from 1)		A523 R525
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005201 extracellular matrix structural constituent
Cellular Component
GO:0005581 collagen trimer

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8txn, PDBe:8txn, PDBj:8txn
PDBsum8txn
PubMed37890775
UniProtP08120|CO4A1_DROME Collagen alpha-1(IV) chain (Gene Name=Col4a1);
Q9VMV5

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