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Receptor Information

>8tx5 Chain D (length=639) Species: 5518 (Fusarium graminearum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ASAPIGSAIPRNNWAVTCDSAQSGNECNKAIDGNKDTFWHTFYGANGDPK
PPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEVYLSSDGTNWGSPV
ASGSWFADSTTKYSNFETRPARYVRLVAITEANGQPWTSIAEINVFQASS
YTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFEGSPGG
ITLTSSWDPSTGIVSDRTSTVTKHDMFCPGISMDGNGQIVVTGGNDAKKT
SLYDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGRVEKNGE
VYSPSSKTWTSLPNAKVNPMLTADKQGLYRSDNHAWLFGWKKGSVFQAGP
STAMNWYYTSGSGDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFG
GSPDYEDSDATTNAHIITLGEPGTSPNTVFASNGLYFARTFHTSVVLPDG
STFITGGQRRGIPTEDSTPVFTPEIYVPEQDTFYKQNPNSIVRAYHSISL
LLPDGRVFNGGGGLCGDCTTNHFDAQIFTPNYLYDSNGNLATRPKITRTS
TQSVKVGGRITISTDSSISKASLIRYGTATHTVNTDQRRIPLTLTNNGGN
SYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRVTQ

Ligand ID

InChI

InChI=1S/Cu/q+2

InChIKey

JPVYNHNXODAKFH-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Cu+2]
CACTVS 3.341	[Cu++]

Formula

Name

COPPER (II) ION

PDB chain

8tx5 Chain D Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8tx5 Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
Resolution	1.93 Å
Binding residue (original residue number in PDB)	Y272 Y495 H496 H581
Binding residue (residue number reindexed from 1)	Y272 Y495 H496 H581
Annotation score	1

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0045480	galactose oxidase activity
GO:0046872	metal ion binding

	Cellular Component
GO:0005576	extracellular region

PDB	RCSB:8tx5, PDBe:8tx5, PDBj:8tx5
PDBsum	8tx5
PubMed
UniProt	P0CS93\|GAOA_GIBZA Galactose oxidase (Gene Name=GAOA)

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Structure of PDB 8tx5 Chain D Binding Site BS01