Structure of PDB 8twv Chain D Binding Site BS01

Receptor Information
>8twv Chain D (length=310) Species: 204038 (Dickeya dadantii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVEN
TQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSF
SNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEW
WIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFIL
PLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILGRLPYTT
YIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRSRLAFPLGFLA
IGCVLVIRFF
Ligand information
Ligand ID3CN
InChIInChI=1S/C3H9N/c1-2-3-4/h2-4H2,1H3
InChIKeyWGYKZJWCGVVSQN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04NCCC
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCCN
FormulaC3 H9 N
Name3-AMINOPROPANE
ChEMBLCHEMBL14409
DrugBank
ZINCZINC000016052656
PDB chain8twv Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8twv Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		E131 F133 F188
Binding residue
(residue number reindexed from 1)		E121 F123 F178
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0042802 identical protein binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0007165 signal transduction
GO:0034220 monoatomic ion transmembrane transport
GO:0042391 regulation of membrane potential
Cellular Component
GO:0016020 membrane
GO:0043005 neuron projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8twv, PDBe:8twv, PDBj:8twv
PDBsum8twv
PubMed38167383
UniProtE0SJQ4

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