Structure of PDB 8th6 Chain D Binding Site BS01
Receptor Information
>8th6 Chain D (length=129) Species:
9606
(Homo sapiens) [
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VMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGDAVYGQKE
IHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQ
TFVLAPEGSVANKFYVHNDIFRYQDEVFG
Ligand information
>8th6 Chain E (length=18) Species:
9606
(Homo sapiens) [
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PQYIFGDFSPDEFNQFFV
Receptor-Ligand Complex Structure
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PDB
8th6
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
Resolution
2.34 Å
Binding residue
(original residue number in PDB)
P6 V11 E14 F15 R17 Q18 L22 M29 R32 F33 N122 K123 F124
Binding residue
(residue number reindexed from 1)
P5 V10 E13 F14 R16 Q17 L21 M28 R31 F32 N112 K113 F114
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:8th6
,
PDBe:8th6
,
PDBj:8th6
PDBsum
8th6
PubMed
38492217
UniProt
Q13283
|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)
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