Structure of PDB 8t2r Chain D Binding Site BS01

Receptor Information
>8t2r Chain D (length=388) Species: 39491 (Agathobacter rectalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNLMEQILSSDNLNRAYLQVVRNKGAEGVDGMKYTELKEHLAKNGETIKG
QLRTRKYKPQPGVPTVTDRFIQQAIAQVLTPIYEEQFHDHSYGFRPNRCA
QQAILTALNIMNDGNDWIVDIDLEKFFDTVNHDKLMTLIGRTIKDGDVIS
IVRKYLVSGNLSPLLANIMLNELDKEMEKRGLNFVRYADDCIIMVGSEMS
ANRVMRNISRFIEEKLGLKVNMTKSKVDRPSGLKYLGFGFYFDPRAHQFK
AKPHAKSVAKFKKRMKELTCRSWGVSNSYKVEKLNQLIRGWINYFKIGSM
KTLCKELDSRIRYRLRMCIWKQWKTPQNQEKNLVKLGIDRNTARRVAYTG
KRIAYVCNKGAVNVAISNKRLASFGLISMLDYYIEKCV
Ligand information
Receptor-Ligand Complex Structure
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PDB8t2r Structural insights into intron catalysis and dynamics during splicing
Resolution3.1 Å
Binding residue
(original residue number in PDB)
N378 R381 R382 V383 Y385 K388 R389 Y392 G397 A398
Binding residue
(residue number reindexed from 1)
N341 R344 R345 V346 Y348 K351 R352 Y355 G360 A361
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003964 RNA-directed DNA polymerase activity
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0006974 DNA damage response

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Molecular Function

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Biological Process
External links
PDB RCSB:8t2r, PDBe:8t2r, PDBj:8t2r
PDBsum8t2r
PubMed37993708
UniProtA0A173ZME3

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