Structure of PDB 8sft Chain D Binding Site BS01

Receptor Information
>8sft Chain D (length=416) Species: 32264 (Tetranychus urticae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSLKILFTALFGPGHLNACLGIGSLLRKRGHQIYFAHFPRHRATIEKHGF
LFISLLDYAEPEFPIVDMLGIIAKFAFERMHKLTPLELFHTFAGMVNGSK
GENYAMMKIVKEYKPDVCLADYLFNMPWMFTVDCPVIPVKSVNPIELYNG
PPALTGCSIHDPPSVREEQLARKSELELESELEKLFAHFNVPLVSYNYAQ
QLGIYIYPGPLDYKELGSPKENWVRLDSSIRSTEISNFELPEKLKDKPGK
LIYVSMGSLASAVTELLTMILTPLANSPHRFIVSTGPNGDSIKLYDNMWG
DKFINQVALLPKVDLFITHGGSNSLIEGLTAGKPLIAIPQFGDQLDNAQR
IADLGLGVRLNLHEFSGEKLLKAIEDVLNDEKINANVARVSEELKKSDSK
DKVISLIEKLARDKKL
Ligand information
Ligand IDUDP
InChIInChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKeyXCCTYIAWTASOJW-XVFCMESISA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)OP(=O)(O)O)O)O
CACTVS 3.370O[CH]1[CH](O)[CH](O[CH]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
CACTVS 3.370O[C@H]1[C@@H](O)[C@@H](O[C@@H]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)O)O)O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC2OC(N1C(=O)NC(=O)C=C1)C(O)C2O
FormulaC9 H14 N2 O12 P2
NameURIDINE-5'-DIPHOSPHATE
ChEMBLCHEMBL130266
DrugBankDB03435
ZINCZINC000004490939
PDB chain8sft Chain D Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8sft Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with kaempferol
Resolution2.75 Å
Binding residue
(original residue number in PDB)		N27 R252 S279 S305 F324 I325 Q327 H340 G342 N344 S345 E348
Binding residue
(residue number reindexed from 1)		N17 R231 S258 S284 F303 I304 Q306 H319 G321 N323 S324 E327
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8sft, PDBe:8sft, PDBj:8sft
PDBsum8sft
PubMed
UniProtT1KUK4

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