Structure of PDB 8sf9 Chain D Binding Site BS01

Receptor Information

>8sf9 Chain D (length=285) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRIPLVGKDSIESKDIGFTLIHEHLRGFSEAVRQQWPHLYNEDEEFRNAV
NEVKRAMQFGVKTIVDPTVMGLGRDIRFMEKVVKATGINLVAGTGIYIYI
DLPFYFLNRSIDEIADLFIHDIKEGIQGTLNKAGFVKIAADEPGITKDVE
KVIKAAAIANKETKVPIITHSNAHNNTGLEQQRILTEEGVDPGKILIGHL
GDTDNIDYIKKIADKGSFIGLDVDKRNETTLRLIKDGYSDKIMISHDIDS
TTLIFEDTIPFLKRNGVNEEVIATIFKENPKKFFS

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

8sf9 Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8sf9 Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
Resolution	1.8 Å
Binding residue (original residue number in PDB)	H22 H24 K137 H199 D256
Binding residue (residue number reindexed from 1)	H22 H24 K137 H199 D247
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.8.1: aryldialkylphosphatase.

Gene Ontology

	Molecular Function
GO:0004063	aryldialkylphosphatase activity
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0016788	hydrolase activity, acting on ester bonds
GO:0046872	metal ion binding

	Biological Process
GO:0009056	catabolic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8sf9, PDBe:8sf9, PDBj:8sf9
PDBsum	8sf9
PubMed
UniProt	Q97VT7\|PHP_SACS2 Aryldialkylphosphatase (Gene Name=php)

[Back to BioLiP]