Structure of PDB 8s9v Chain D Binding Site BS01

Receptor Information
>8s9v Chain D (length=518) Species: 1148 (Synechocystis sp. PCC 6803) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARKVTTRWKITGTLIAETPLHIGGVGGDADTDLALAVNGAGEYYVPGTSL
AGALRGWMTQLLNNDESQIKDLWGDHLDAKRGASFVIVDDAVIHIPNNAD
VEIREGVGIDRHFGTAANGFKYSRAVIPKGSKFKLPLTFDSQDDGLPNAL
IQLLCALEAGDIRLGAAKTRGLGRIKLDDLKLKSFALDKPEGIFSALLDQ
GKKLDWNQLKANVTYQSPPYLGISITWNPKDPVMVKAEGDGLAIDILPLV
SQVGSDVRFVIPGSSIKGILRTQAERIIRTICQSNGSEKNFLEQLRINLV
NELFGSASLSQKQNGKDIDLGKIGALAVNDCFSSLSMTPDQWKAVENATE
MTGNLQPALKQATGYPNNISQAYKVLQPAMHVAVDRWTGGAAEGMLYSVL
EPIGVTWEPIQVHLDIARLKNYYHGKEEKLKPAIALLLLVLRDLANKKIP
VGYGTNRGMGTITVSQITLNGKALPTELEPLNKTMTCPNLTDLDEAFRQD
LSTAWKEWIADPIDLCQQ
Ligand information
>8s9v Chain F (length=37) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acugaaacuguaguagaaccaaucggggucgucaaua
.....................................
Receptor-Ligand Complex Structure
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PDB8s9v RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
G24 T49 S50 R56 D76 H77 G83 S85 E106 G107 V108 I110 R112 K122 Y123 A167 A168 K169 T170 R171 K237 S265 S266 K268 G269 R272 G306 S307 A308 S309 K323 G325 M381 H382 V383 V385 R387 G391 L397 Y398 G453 Y454 G455 N457 R458
Binding residue
(residue number reindexed from 1)
G23 T48 S49 R55 D75 H76 G82 S84 E105 G106 V107 I109 R111 K121 Y122 A166 A167 K168 T169 R170 K236 S264 S265 K267 G268 R271 G305 S306 A307 S308 K322 G324 M380 H381 V382 V384 R386 G390 L396 Y397 G452 Y453 G454 N456 R457
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:8s9v, PDBe:8s9v, PDBj:8s9v
PDBsum8s9v
PubMed38637512
UniProtQ6ZED3

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