Structure of PDB 8pi5 Chain D Binding Site BS01

Receptor Information
>8pi5 Chain D (length=53) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKAMKGIVEQCCTSICSLYQLEN
YCN
Ligand information
Ligand IDRCO
InChIInChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
InChIKeyGHMLBKRAJCXXBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1cc(cc(c1)O)O
ACDLabs 10.04
CACTVS 3.341		Oc1cccc(O)c1
FormulaC6 H6 O2
NameRESORCINOL;
1,3-BENZENEDIOL;
1,3-DIHYDROXYBENZENE
ChEMBLCHEMBL24147
DrugBankDB11085
ZINCZINC000000002028
PDB chain8pi5 Chain D Residue 103 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8pi5 Molecular engineering of insulin for recombinant expression in yeast.
Resolution1.66 Å
Binding residue
(original residue number in PDB)		L11 C38 I42 C43
Binding residue
(residue number reindexed from 1)		L11 C38 I42 C43
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:8pi5, PDBe:8pi5, PDBj:8pi5
PDBsum8pi5
PubMed37880066
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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