Structure of PDB 8pc5 Chain D Binding Site BS01

Receptor Information
>8pc5 Chain D (length=94) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>8pc5 Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctag
caccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaagg
ggattactccctagtctccaggcacgtgtcagatatatacatccgat
Receptor-Ligand Complex Structure
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PDB8pc5 Multivalency of nucleosome recognition by LEDGF.
Resolution3.02 Å
Binding residue
(original residue number in PDB)		R30 Y39 I51 S53 R83
Binding residue
(residue number reindexed from 1)		R2 Y11 I23 S25 R55
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8pc5, PDBe:8pc5, PDBj:8pc5
PDBsum8pc5
PubMed37615563
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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