Structure of PDB 8ol1 Chain D Binding Site BS01
Receptor Information
>8ol1 Chain D (length=95) Species:
9606
(Homo sapiens) [
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KRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASR
LAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS
Ligand information
>8ol1 Chain I (length=145) [
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tggagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcctg
Receptor-Ligand Complex Structure
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PDB
8ol1
Nuclear degradation of cGAS is essential for immune homeostasis
Resolution
3.5 Å
Binding residue
(original residue number in PDB)
K30 S32 R33 G53 I54 S55 S56 T88
Binding residue
(residue number reindexed from 1)
K1 S3 R4 G24 I25 S26 S27 T59
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0030527
structural constituent of chromatin
GO:0046982
protein heterodimerization activity
Cellular Component
GO:0000786
nucleosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:8ol1
,
PDBe:8ol1
,
PDBj:8ol1
PDBsum
8ol1
PubMed
38418882
UniProt
Q93079
|H2B1H_HUMAN Histone H2B type 1-H (Gene Name=H2BC9)
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