Structure of PDB 8hey Chain D Binding Site BS01

Receptor Information
>8hey Chain D (length=1270) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FEAIFGTFCNRLEWVYFLTSGLAAAAHAIKFHDLNKLTTGKMLFHVQVPR
VASGAGLPTSRQTTIMVTKYSEKSPITIPFELSAACLTYLRETFEGTILD
KILNVEAMHTVLRALKNTADAMERGLIHSFLQTLLRKAPPYFVVQTLVEN
ATLARQALNRIQRSNILQSFKAKMLATLFLLNRTRDRDYVLKFLTRLAEA
ATDSILDNPTTYTTSSGAKISGVMVSTANVMQIIMSLLSSHITKETVSAP
ATYGNFVLSPENAVTAISYHSILADFNSYKAHLTSGQPHLPNDSLSQAGA
HSLTPLSMDVIRLGEKTVIMENLRRVYKNTDTKDPLERNVDLTFFFPVGL
YLPEDRGYTTVESKVKLNDTVRNALPTTAYLLNRDRAVQKIDFVDALKTL
CHPVLHEPAPCLQTFTEPMGGAARRIPHFYRVRREVPRTVNEMKQDFVVT
DFYKVGNITLYTELHPFFDFTHCQLCTPRIVIGNLPDGLAPGPFHELRTW
EIMEHMRLRPPPDYEETLRLFKTTVTSPNYPELCYLVDVLVHGNVDAFLL
IRTFVARCIVNMFHTRQLLVFAHSYALVTLIAEHLADGALPPQLLFHYRN
LVAVLRLVTRISALPGLNNGQLAEEPLSAYVNALHDHRLWPPFVTHLPRN
MEGVQVVADRQPLNPANIEARHHGVSDVPRLGAMDADEPLFVDDYRATDD
EWTLQKVFYLCLMPAMTNNRACGLGLNLKTLLVDLFYRPAFLLMPIAAQR
QAVGEMLTELVEDVATDAHTPLLQACRELFLAVQFVGEHVKVLEVRAPLD
HAQRQGLPDFISRQHVLYNGCCVVTAPKTLIEYSLPVPFHRFYSNPTICA
ALSDDIKRYVTEFPHYHRHDGGFPLPTAFAHEYHNWLRSPFSRYSATCPN
VLHSVMTLAAMLYKISPVSLVLQTKAHIHPGFALTAVRTDTFEVDMLLYS
GKSCTSVIINNPIVTKEERDISTTYHVTQNINTVDMGLGYTSNTCVAYVN
RVRTDMGVRVQDLFRVFPMNVYRHDEVDRWIRHAAGVERPQLLDTETISM
LTFGSMSERNAAATVHGQKAACELILTPVTMDVNYFKIPNNPRGRASCML
AVDPYDTEAATKAIYDHREADAQTFAATHNPWASQAGCLSDVLYNTRHRE
RLGYNSKFYSPCAQYFNTEEIIAANKTLFKTIDEYLLRAKDCIRGDTDTQ
YVCVEGTEQLIENPCRLTQEALPILSTTTLALMETKLKGGAGAFATSETH
FGNYVVGEIIPLQQSMLFNS
Ligand information
>8hey Chain T (length=23) Species: 10359 (Human betaherpesvirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LFNDKCAFKLDLLRMVAVSRTRR
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hey Cryo-electron microscopy structures of capsids and in situ portals of DNA-devoid capsids of human cytomegalovirus.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		G750 V751 S752 V754 L757 K805 V809 Y813 M820 P821 F880 L881 Q884
Binding residue
(residue number reindexed from 1)		G674 V675 S676 V678 L681 K729 V733 Y737 M744 P745 F780 L781 Q784
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid
GO:0039622 T=16 icosahedral viral capsid

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8hey, PDBe:8hey, PDBj:8hey
PDBsum8hey
PubMed37041152
UniProtA0A1U8QPG3

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