Structure of PDB 8h2c Chain D Binding Site BS01

Receptor Information

>8h2c Chain D (length=341) Species: 197 (Campylobacter jejuni) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QIGNFNTDKKVFIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQTYTP
DSLTLNSDKEDFIIKGGLWDKRKLYELYESAKTPYEWHSQIFETAQNEGI
LCFSSPFAKEDVEFLKRFDPIAYKIASFEANDENFVRLIAKEKKPTIVST
GIATEEELFKICEIFKEEKNPDLIFLKCTSAYPAAIEDMNLKGIVSLKEK
FNVEVGLSDHSFGFLAPVMAVALGARVIEKHFMLDKSIESEDSKFSLDFD
EFKAMVDAVRQAESALGDDKLDLDEKALKNRVFARSLYASKDIKKGEIFS
EENVKSVRPSFGLHPKFYQELLGKKATKDIKFGDALKQGDF

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

8h2c Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8h2c Structural analysis of the pseudaminic acid synthase PseI from Campylobacter jejuni.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	E17 H211 H232
Binding residue (residue number reindexed from 1)	E16 H210 H231
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.5.1.97: pseudaminic acid synthase.

Gene Ontology

	Molecular Function
GO:0016740	transferase activity
GO:0046872	metal ion binding
GO:0047444	N-acylneuraminate-9-phosphate synthase activity

	Biological Process
GO:0016051	carbohydrate biosynthetic process
GO:0070085	glycosylation

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Molecular Function

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Biological Process

External links

PDB	RCSB:8h2c, PDBe:8h2c, PDBj:8h2c
PDBsum	8h2c
PubMed	36283338
UniProt	Q0P8U0\|PSEI_CAMJE Pseudaminic acid synthase (Gene Name=pseI)

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