Structure of PDB 8h1r Chain D Binding Site BS01

Receptor Information
>8h1r Chain D (length=789) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADYSHLDWIPREKLTAAQLAEIGPYCGGSYIEPVRPGMPTYVSAKASRYE
IATLAGDVVLRQGSMQVEGDEANLHQLENRGELVGNVKLRDKGMLVVGDH
AQVQLDNGEAQVDNAEYVIHKAHARGSALYAKRSENAIIMLKDGTYTRCE
PSSNAWTLKGNNVKLNPATGFGTATNATLRVKDFPVFYTPYIYFPIDDRR
QSGFLPPSFSSTSDTGFTLVTPYYFNLAPNYDATLYPRYMAKRGMMLEGE
FRYLTHSSEGIVNAAYLNDKDDHREGFPDYSKDRWLYGLKNTTGLDSRWL
AEVDYTRISDPYYFQDLDTDLGVGSTTYVNQRGTLTYRGDTFTGRLNAQA
YQLATTTDVTPYDRLPQITFDGFLPYNPGGMQFTYGTEFVRFDRDLDENI
YFNSIRGKRPDASLQGLARATGDRMHLEPGMSLPMTRSWGYVTPTLKYLY
TKYDLDLDSQGKTDLNKRDESFDSNQDRSLPLVKVDSGLYFDRDTTFAGT
PFRQTLEPRAMYLYVPYKDQDSLPVFDTSEPSFSYDSLWRENRFTGKDRI
GDANQLSLGVTSRFIEENGFERASISAGQIYYFRDRRVQLPGLTEKDLKR
LNLDGLDNDSWRSPYAFAGQYRFNRDWRINSDFNWNPNTSRTESGSAIFH
YQPEVDPGKVVNVGYRYRADARRFDSSRGTFRYGNENDIIKQHDFSVIWP
LVPQWSVLARWQYDYNKNRTLEAFGGFEYDSCCWKLRLINRYWLDVDDDA
FLVQSEKADRGIFLQIVLKGLGGIVGTEMFLDKGIQGYR
Ligand information
>8h1r Chain F (length=12) Species: 83333 (Escherichia coli K-12) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GLKGPLYFPPAD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8h1r Lipoprotein sorting to the cell surface via a crosstalk between the Lpt and Lol pathways during outer membrane biogenesis
Resolution2.98 Å
Binding residue
(original residue number in PDB)		D319 R321 Q322 S323 G324 Y345 P350 N351 Y352 T355 E371 R373 Y374 L375 T376 H377 G898 G899 I900 V901
Binding residue
(residue number reindexed from 1)		D198 R200 Q201 S202 G203 Y224 P229 N230 Y231 T234 E250 R252 Y253 L254 T255 H256 G772 G773 I774 V775
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0015920 lipopolysaccharide transport
GO:0043165 Gram-negative-bacterium-type cell outer membrane assembly
GO:0061024 membrane organization
Cellular Component
GO:0009279 cell outer membrane
GO:0019867 outer membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8h1r, PDBe:8h1r, PDBj:8h1r
PDBsum8h1r
PubMed
UniProtQ9I5U2|LPTD_PSEAE LPS-assembly protein LptD (Gene Name=lptD)

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