Structure of PDB 8gj2 Chain D Binding Site BS01

Receptor Information

>8gj2 Chain D (length=360) Species: 83333 (Escherichia coli K-12)

SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGK
TSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKV
EDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVK
FLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPR
ALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALS
LVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAA
LGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEM
TLLRALAFHP

Ligand information

>8gj2 Chain Y (length=29)

ttttttcgatcgtatgttgtaactatctc

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8gj2 Structural characterisation of the complete cycle of sliding clamp loading in E. coli
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): K100 V101 H134
• Binding residue (residue number reindexed from 1): K99 V100 H133

Enzymatic activity

• Enzyme Commision number: 2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003887 DNA-directed DNA polymerase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006260 DNA replication
• GO:0006261 DNA-templated DNA replication
• GO:0071897 DNA biosynthetic process
• GO:0075523 viral translational frameshifting

Cellular Component

• GO:0009360 DNA polymerase III complex
• GO:0030894 replisome
• GO:0043846 DNA polymerase III, clamp loader complex

External links

• PDB: RCSB:8gj2, PDBe:8gj2, PDBj:8gj2
• PDBsum: 8gj2
• UniProt: P06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)