Structure of PDB 8g9s Chain D Binding Site BS01

Receptor Information
>8g9s Chain D (length=283) Species: 486 (Neisseria lactamica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIEKRYDFVFLFDVQDGNPNGDPDAGNLPRIDPQTGEGLVTDVCLKRKVR
NFIQMTQNDEHHDIFIREKGILNNLIDEAHEQENVKGKEKGEKTEAARQY
MCSRYYDIRTFGAVMTTGKNAGQVRGPVQLTFSRSIDPIMTLEHSITRMA
VTNEKDASETGDNRTMGRKFTVPYGLYRCHGFISTHFAKQTGFSENDLEL
FWQALVNMFDHDHSAARGQMNARGLYVFEHSNNLGDAPADSLFKRIQVVK
KDGVEVVRSFDDYLVSVDDKNLEETKLLRKLGG
Ligand information
>8g9s Chain O (length=42) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auugaaacagggucagcuugccguagguggcaucgcccucgu
..........................................
Receptor-Ligand Complex Structure
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PDB8g9s Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
G22 D23 D25 V44 K47 R48 R51 G113 Q124 V125 R126 Q130 I147 T148 R149 M150 N164 S215 A216 R218
Binding residue
(residue number reindexed from 1)
G21 D22 D24 V43 K46 R47 R50 G112 Q123 V124 R125 Q129 I146 T147 R148 M149 N163 S214 A215 R217
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043571 maintenance of CRISPR repeat elements

View graph for
Biological Process
External links
PDB RCSB:8g9s, PDBe:8g9s, PDBj:8g9s
PDBsum8g9s
PubMed38242128
UniProtD0W8X6

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