Structure of PDB 8f1e Chain D Binding Site BS01

Receptor Information
>8f1e Chain D (length=171) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNF
GEIKFDVWDTAGLEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHR
DLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYN
FEKPFLWLARKLAGNPQLEFV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8f1e Chain D Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8f1e Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.
Resolution3.28 Å
Binding residue
(original residue number in PDB)		T26 T44
Binding residue
(residue number reindexed from 1)		T18 T36
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006913 nucleocytoplasmic transport

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Molecular Function
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Biological Process
External links
PDB RCSB:8f1e, PDBe:8f1e, PDBj:8f1e
PDBsum8f1e
PubMed37450495
UniProtP32835|GSP1_YEAST GTP-binding nuclear protein GSP1/CNR1 (Gene Name=GSP1)

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