Structure of PDB 8dy7 Chain D Binding Site BS01

Receptor Information
>8dy7 Chain D (length=1253) Species: 54571 (Streptomyces venezuelae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDVNFFDELRIGLATADDIRQWSHGEVKKPETINYRTLKPEKDGLFCEKI
FGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPV
THIWYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMITYVDDERRTRDLPSL
EAHVSVERQQIENRRDSDLEARAKKLENDLGELEAEGAKADVRRKVREGA
EREMKQLRDRAQREIDRLDEVWSRFKNLKVQDLEGDELLYRELRDRFGTY
FDGSMGAAALQKRLESFDLEEEAERLREIIRTGKGQKKTRALKRLKVVSA
FLQTANSPKGMVLDCVPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRN
NRLKRLLDLGAPEIIVNNEKRMLQEAVDALFDNGRRGRPVTGPGNRPLKS
LSDMLKGKQGRFRQNLLGKRVDYSARSVIVVGPQLKLHQCGLPKAMALEL
FKPFVMKRLVDLNHAQNIKSAKRMVERGRTVVYDVLEEVIAEHPVLLNRA
PTLHRLGIQAFEPQLVEGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEA
QAEARILMLSSNNILKPADGRPVTMPTQDMVLGLFFLTTDGELRDTKGEG
RAFGSTAEAIMAFDAGELALQSQIDIRFPVGTVAPRGWVPPVTEEGEPEW
QQGDSFRLRTSLGRALFNELLPEDYPFVDYSVGKKQLSEIVNDLAERYPK
VIVAATLDNLKAAGFYWATRSGVTVAISDVVVPEAKKAIVKGYEEQDEKV
QKQYERGLITKEERTQELIAIWTKATNEVAEAMNANFPKTNPIFMMVDSG
ARGNMMQMRQIAGMRGLVSNAKNETIPRPIKASFREGLTVLEYFISTHGA
RKGLADTALRTADSGYLTRRLVDVSQDVIIREEDCGTERGLKLRIAERGA
DGVLRKTDDVETSVYARMLAEDVVVDGKVIAPANVDLGDVLIDALVGAGV
EEVKTRSVLTCESAVGTCAFCYGRSLATGKLVDIGEAVGIIAAQSIGEPG
TQLTMDITQGLPRVVELFEARQPKGVAPISEAAGRVRIEETEKTKKIVVT
PDDGTDETAFPISKRARLLVGEGDHVEVGQKLTVGATNPHDVLRILGQRA
VQVHLVAEVQKVYNSQGVSIHDKHIEIIIRQMLRRVTIIESGDAELLPGE
LVERSKFETENRRVVTEGGHPASGRPQLMGITKASLATESWLSAASFQET
TRVLTDAAINAKSDSLIGLKENVIIGKLIPAGTGLSRYRNIRVEPTEEAK
AAM
Ligand information
>8dy7 Chain P (length=71) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aggccgctgctgctcaagaggggttcgcgggacggcatcggccaattggc
ccggtgtgtcgcacgatctgg
Receptor-Ligand Complex Structure
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PDB8dy7 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Resolution3.18 Å
Binding residue
(original residue number in PDB)
Q1210 E1211
Binding residue
(residue number reindexed from 1)
Q1198 E1199
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8dy7, PDBe:8dy7, PDBj:8dy7
PDBsum8dy7
PubMed36888660
UniProtF2RIS6

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