Structure of PDB 8dvx Chain D Binding Site BS01

Receptor Information

>8dvx Chain D (length=104) Species: 9823 (Sus scrofa)

GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFSYTD
ANKNKGITWGEETLMEYLENPKKYIPGTKMIFAGIKKKGEREDLIAYLKK
ATNE

Ligand information

• Ligand ID: FC6
• InChI: InChI=1S/6CN.Fe/c6*1-2;
• InChIKey: HCMVSLMENOCDCK-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C(#N)[Fe](C#N)(C#N)(C#N)(C#N)C#N
  ACDLabs 10.04
  CACTVS 3.341: N#C[Fe](C#N)(C#N)(C#N)(C#N)C#N
• Formula: C6 Fe N6
• Name: HEXACYANOFERRATE(3-);
  FERRI(III)HEXACYANIDE
• PDB chain: 8dvx Chain A Residue 202

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8dvx Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
• Resolution: 1.5 Å
• Binding residue (original residue number in PDB): K13 K87 E90
• Binding residue (residue number reindexed from 1): K13 K87 E90
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
• GO:0006915 apoptotic process

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:8dvx, PDBe:8dvx, PDBj:8dvx
• PDBsum: 8dvx
• PubMed: 37443314
• UniProt: P62895|CYC_PIG Cytochrome c (Gene Name=CYCS)