Structure of PDB 8d1n Chain D Binding Site BS01

Receptor Information
>8d1n Chain D (length=338) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVTYTARVAKARFGGFSKLLLLWRGSIYKLLWRELLCFLGLFMALSAAYR
FVLTEEQKRYFEKLVLYCDRYASLIPVSFVLGFYVTLVVHRWWNQYLSMP
LTDALMCVVVGTVHGHDERGRLYRRTLMRYAGLSGVLILRSVSTAVFKRF
PTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFCNLAAQARREGRI
RDNGAFKLLLEELNVFRSKCGMLFHYDWISVPLVYTQVVTIAVYSYFLAC
LIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGED
DDDFETNFLIDRCFQVSMLAVDEMYDDLAMLEKDLYWD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8d1n Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d1n Structures and gating mechanisms of human bestrophin anion channels.
Resolution1.93 Å
Binding residue
(original residue number in PDB)		Q293 N296 D301 D304
Binding residue
(residue number reindexed from 1)		Q292 N295 D300 D303
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity

View graph for
Molecular Function
External links
PDB RCSB:8d1n, PDBe:8d1n, PDBj:8d1n
PDBsum8d1n
PubMed35789156
UniProtE1BF86|BEST2_BOVIN Bestrophin-2 (Gene Name=BEST2)

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