Structure of PDB 8csq Chain D Binding Site BS01

Receptor Information
>8csq Chain D (length=232) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERGWSGNSWGGISLGPPDPGPCGETYEDFDTRILEVRNVFKSIRVLVAVG
NGKGAAGFSIGKATDRMDAFRKAKNRAVHHLHYIERYEDHTIFHDISLRF
KRTHIKMKKQPKGYGLRCHRAIITICRLIGIKDMYAKVSGSINMLSLTQG
LFRGLSRQETHQQLADKKGLHVVEIREECGPLPIVVASPRGPLRKDPEPE
DEVPDVKLDWEDVKTAQGMKRSVWSNLKRAAT
Ligand information
>8csq Chain A (length=802) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucaaauaaagcuaaaaaaauagacuacgaaaguggcuuuaacauau
cugaacacacaauagcuaagacccaaacugggauuagauaccccacuaug
cuuagcaacaguuaaaucaacaaaacugcucgccagaacacuacgagcca
cagcuuaaaacucaaaggaccuggcggugcuucauaucccucuagaggag
ccuguucuguaaucgauaaaccccgaucaaccucaccaccucuugcucag
ccuauauaccgccaucuuaacccugaugaaggcuacaaaguacguuaggu
caagguguagcccaugagguggcaagaaaugggcuacauuuucuacccca
gaaaauuuagcaguaaacugagaggcuuaguugaacagggcccugaagcg
cgucgucacccuccucaaguauacuucaaaggacauuuaacuaaaacccc
uacgcauuuauauagaggagacaagucguaaaguguacuggaaagugcac
uu
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<..<.<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>>........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<.....<<<<<<..............<<....>>.>>>>>>.....>
>>>...>>>>.....<<<<<...<<...<<<<.........>>>>...>>
>>>>>.<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<..
..>>>>.....>>..>>>>>>.....<<<<<<<<...<<<.<<<<<.<<<
<<<<<<<<......<<................>>.<<<<<<<.......<
<.<<<..<<<<<<<.<...<<<<<.....>>>.......>>..>.>.>>>
...>>>>>>>>....>>>>>>>..>>>.>>>>>>>.>...<<<<.....>
>>>..>>>>>.....<<<<<<<...>>>>>>>.....>>>...>>>>>>>
>..<<.....<<<<<<..<<<<<......<<<...<<<.....>>>..>>
>.......>>>>>.>>>>>>......>>..<<<<<<<<<....>>>>>>>
>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8csq Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		R191 S194 G195 N196 R226 V228 R242 F256 K260 K270 R274 R297 F298 K299 R300 R315 C316 H317 R318 Y333 A334 K335 S339 I340 N341 R351 R355 K405 W408 R419 S420 V421 W422 S423 R427
Binding residue
(residue number reindexed from 1)		R2 S5 G6 N7 R37 V39 R44 F58 K62 K72 R76 R99 F100 K101 R102 R117 C118 H119 R120 Y135 A136 K137 S141 I142 N143 R153 R157 K207 W210 R221 S222 V223 W224 S225 R229
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8csq, PDBe:8csq, PDBj:8csq
PDBsum8csq
PubMed36482135
UniProtP82675|RT05_HUMAN Small ribosomal subunit protein uS5m (Gene Name=MRPS5)

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