Structure of PDB 8cnz Chain D Binding Site BS01

Receptor Information
>8cnz Chain D (length=261) Species: 39152 (Methanococcus maripaludis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPMIIMEKGLLEKYNSLLEFFKNKKVIVAYSGGVDSTLISKIASDNAQTL
AVTIDNGFFSENVIKKAENRAKKYNIPQKTIKIDYLNEITSKDLENRCYN
CKKRIAEELKRIKNELNYDIIVDGTIYDDIFEDRPGIKAFNESNIISPLS
NLKFSKNDVFELSNYLKIDIPKKDTCMATRILSAPISKENMAKSNLAEEF
IKLNFHIESYLRVRYLENIAIIELTKNESEKIFDNDSIERINTELKKIGF
EKVVLDLNFKG
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8cnz Chain D Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cnz Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		F56 C96 C99 C174
Binding residue
(residue number reindexed from 1)		F58 C98 C101 C176
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016783 sulfurtransferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:8cnz, PDBe:8cnz, PDBj:8cnz
PDBsum8cnz
PubMed38100250
UniProtQ6LXV7

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