Structure of PDB 8c20 Chain D Binding Site BS01

Receptor Information
>8c20 Chain D (length=355) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLRLSDHLLANYGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIW
YRQYWTDEFLQWTPEDFDNTKLSIPTDSIWVPDILINEFVDVGKSPNIPY
VYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN
ITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYV
IIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSV
FLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHQRPVP
DWLRHLVLDRIAWEVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWS
IWHSS
Ligand information
Ligand IDSRO
InChIInChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
InChIKeyQZAYGJVTTNCVMB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1cc2c(cc1O)c(c[nH]2)CCN
ACDLabs 10.04Oc1cc2c(cc1)ncc2CCN
CACTVS 3.341NCCc1c[nH]c2ccc(O)cc12
FormulaC10 H12 N2 O
NameSEROTONIN;
3-(2-AMINOETHYL)-1H-INDOL-5-OL
ChEMBLCHEMBL39
DrugBankDB08839
ZINCZINC000000057058
PDB chain8c20 Chain D Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c20 UCSF ChimeraX: Structure visualization for researchers, educators, and developers
Resolution3.5 Å
Binding residue
(original residue number in PDB)		F199 I201
Binding residue
(residue number reindexed from 1)		F185 I187
Annotation score1
External links
PDB RCSB:8c20, PDBe:8c20, PDBj:8c20
PDBsum8c20
PubMed
UniProtP23979|5HT3A_MOUSE 5-hydroxytryptamine receptor 3A (Gene Name=Htr3a)

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