Structure of PDB 8bav Chain D Binding Site BS01

Receptor Information
>8bav Chain D (length=257) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLHK
VKQQFMTTIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDA
DSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRL
DLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEG
PEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQKSELALC
LGLKINP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8bav Chain D Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bav Calmodulin type regulator (Homo sapiens) with peptide ligand
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D118 D120 S122 F124 E129
Binding residue
(residue number reindexed from 1)		D99 D101 S103 F105 E110
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0099509 regulation of presynaptic cytosolic calcium ion concentration
GO:1900271 regulation of long-term synaptic potentiation
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0030425 dendrite
GO:0030658 transport vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0043195 terminal bouton
GO:0045202 synapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bav, PDBe:8bav, PDBj:8bav
PDBsum8bav
PubMed38593081
UniProtO76038|SEGN_HUMAN Secretagogin (Gene Name=SCGN)

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