Structure of PDB 7z6e Chain D Binding Site BS01

Receptor Information
>7z6e Chain D (length=525) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHNFERMKIKTPTKCGHCTSILIGLDRQGLFCQSCQYACHVSCAERVSQS
CPVPEPLGIDPTRGVGTAYEGLVKTPRAGGVRKGWQTAYVVVCDFKLYLY
DCQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFRVTTTQIL
NSSSEYSSSSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFL
VKEVFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVG
GEKENKQRCVETVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKWI
KVNDTKGCHLLAVGTNNPGGRAGFFAVAFKKSVTIFQIDRSEKRHKKWKD
LAMPGTPQSIAIFNGRLYVGFSHSFRSWSLVGVQHISLVNMEDTSLQFLN
QQTSYEAKLIVNVPGSPDEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAK
YFAYHEPYLCVFSENEVDIFNVTLAEWVQTINLRSAKPLSGDGILSTCLC
NDSPIFVLLQNVLQDQDSIEVPVNL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7z6e Chain D Residue 1601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7z6e Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase.
Resolution2.14 Å
Binding residue
(original residue number in PDB)		C971 C974 H996 C999
Binding residue
(residue number reindexed from 1)		C15 C18 H40 C43
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
External links
PDB RCSB:7z6e, PDBe:7z6e, PDBj:7z6e
PDBsum7z6e
PubMed36854301
UniProtO01583|MRCK_CAEEL Serine/threonine-protein kinase mrck-1 (Gene Name=mrck-1)

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