Structure of PDB 7xyb Chain D Binding Site BS01

Receptor Information
>7xyb Chain D (length=1338) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFDAIRIGLASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPV
KDYECLCGKYKRLKHRGVICEKCGVEVALAKVRRERMGHIELASPVAHIW
FLKSLPSRIGLLLDMTLRDIERVLYFESYVVIDPGMTTLEKGQLLNDEQY
FEALEEFGDDFDARMGAEAVHELLNAIDLEHEIGRLREEIPQTNSETKIK
KLSKRLKLMEAFQGSGNKPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDL
NDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRA
ITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQ
CGLPKKMALELFKPFIFGKLEGRGMATTIKAAKKMVERELPEVWDVLAEV
IREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQ
MAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVMGLYYMTR
EAINAKGEGMAFADLQEVDRAYRSGQASLHARVKVRINEKIKGEDGQLTA
NTRIVDTTVGRALLFQVVPAGLPFDVVNQSMKKKAISKLINHCYRVVGLK
DTVIFADQLMYTGFAYSTISGVSIGVNDFVIPDEKARIINAATDEVKEIE
SQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMANLSKEKVVDREGKEVD
QESFNSMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFRE
GLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEIDCG
TEHGLLMSPHIEGGDVVEPLGERVLGRVIARDVFKPGSDEVIVPAGTLID
EKWVDFLEVMSVDEVVVRSPITCETRHGICAMCYGRDLARGHRVNIGEAV
GVIAAQSIGEPGTQLTADNVQVKNGGTIRLHNLKHVVRADGALVAVSRSG
ELAVADDFGRERERYKLPYGAVISVKEGDKVDPGAIVAKWDPHTHPIVTE
VDGTVAFVGMEEGITVKRQTDELTGLTNIEVMDPKDRPAAGKDIRPAVKL
IDAAGKDLLLPGTDVPAQYFLPANALVNLTDGAKVSIGDVVARIPQTGGL
PRVADLFEARRPKEPSILAEISGTISFGKETKGKRRLVITPNDGSDPYEE
LIPKWRHLNVFEGEQVNRGEVISDGPSNPHDILRLLGVSSLAKYIVNEIQ
DVYRLQGVKINDKHIETILRQMLRKVEVSESGDSSFIKGDQVELTQVLEE
NEQLGTEDKFPAKYERVLLGITKASLSTESFISAASFQETTRVLTEAAVT
GKRDFLRGLKENVVVGRLIPAGTGLAYHSERKRQRDLG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xyb Structural basis of AlpA-dependent transcription antitermination.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		R425 D462 D464
Binding residue
(residue number reindexed from 1)		R410 D447 D449
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xyb, PDBe:7xyb, PDBj:7xyb
PDBsum7xyb
PubMed35871295
UniProtQ9HWC9|RPOC_PSEAE DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

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