Structure of PDB 7wm3 Chain D Binding Site BS01

Receptor Information
>7wm3 Chain D (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
REKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGF
GFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKL
FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD
PVDKIVLQKYHTINGHNAEVRKALSRQEM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wm3 Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition.
Resolution1.62 Å
Binding residue
(original residue number in PDB)
K113 F115 G117 G118 R147 R153 F155 F157 E183 R185 R190 Q191 M193
Binding residue
(residue number reindexed from 1)
K99 F101 G103 G104 R133 R139 F141 F143 E169 R171 R176 Q177 M179
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7wm3, PDBe:7wm3, PDBj:7wm3
PDBsum7wm3
PubMed36528084
UniProtP22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (Gene Name=HNRNPA2B1)

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