Structure of PDB 7wku Chain D Binding Site BS01
Receptor Information
>7wku Chain D (length=302) Species:
1586324
(Porcine deltacoronavirus) [
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SAGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGD
QWTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPD
YKFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGY
TLKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYY
TDNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTN
MSYIMGLSQTARVPVERILNTIIQLTTNRGACIMGSYFECDWTPEMVYNQ
AP
Ligand information
>7wku Chain M (length=5) Species:
32630
(synthetic construct) [
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gAVLa
Receptor-Ligand Complex Structure
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PDB
7wku
The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
L27 H41 F139 G142 C144 H162 H163 I164 E165 F166 D186 E188 I190
Binding residue
(residue number reindexed from 1)
L28 H42 F140 G143 C145 H163 H164 I165 E166 F167 D187 E189 I191
Enzymatic activity
Enzyme Commision number
2.1.1.57
: methyltransferase cap1.
3.4.19.12
: ubiquitinyl hydrolase 1.
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
Gene Ontology
Molecular Function
GO:0008233
peptidase activity
Biological Process
GO:0019082
viral protein processing
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Molecular Function
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Biological Process
External links
PDB
RCSB:7wku
,
PDBe:7wku
,
PDBj:7wku
PDBsum
7wku
PubMed
35336895
UniProt
A0A140ESF0
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