Structure of PDB 7vze Chain D Binding Site BS01
Receptor Information
>7vze Chain D (length=91) Species:
9606
(Homo sapiens) [
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DNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNE
GDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRP
Ligand information
>7vze Chain H (length=5) Species:
333760
(Human papillomavirus 16) [
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RETQL
Receptor-Ligand Complex Structure
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PDB
7vze
Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein.
Resolution
2.882 Å
Binding residue
(original residue number in PDB)
R527 F528 G529 F530 N531 V532 K533 Q538 H579 D580 I586
Binding residue
(residue number reindexed from 1)
R15 F16 G17 F18 N19 V20 K21 Q26 H67 D68 I74
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:7vze
,
PDBe:7vze
,
PDBj:7vze
PDBsum
7vze
PubMed
35089587
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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