Structure of PDB 7utn Chain D Binding Site BS01

Receptor Information
>7utn Chain D (length=397) Species: 32630 (synthetic construct) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAVVYVISKSGKPLMPTTRCGHVRILLKEGKARVVERKPFTIQLTYESAE
ETQPLVLGIDPGRTNIGMSVVTESGESVFNAQIETRNKDVPKLMKDRKQY
RMAHRRLKRRCKRRRRAKAAGTAFEEGEKQRLLPGCFKPITCKSIRNKEA
RFNNRKRPVGWLTPTANHLLVTHLNVVKKVQKILPVAKVVLELNRFSFMS
VLNQIIPYLADQLADMFPGNFCVTSGQDTYLFREEHGIPKDHYLDAYCIA
CSALTDAKKVSSPKGRPYMVHQFRRHDRQACHKANLNRSYYMGGKLVATN
RHKAMDQKTDSLEEYRAAHSAADVSKLTVKHPSAQYKDMSRIMPGSILVS
GEGKLFTLSRSEGRNKGQVNYFVSTEGIKYWARKCQYLRNNGGLQIY
Ligand information
>7utn Chain C (length=184) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaaagagugaacgagaggcucuuccaacuuagguugaaagagcacaggcu
gagacauucguaaggccgaaagaccggacgcacccugggauuuccccagu
ccccggaacugcauagcggaugccaguugauuaucagauaagccaggggg
aacaaucaccucucuguaucagagagaguuuuac
.................<<<<<<.<<<<<..>>>>>.>>>>>>...<<<.
..<.<<<<<<<..<<.<....>.>>....<<<.<<.<<<<<..((((.>>
>>>.>>...>>>...>>>>>>>.>...<<<<.>>>>.....>>>..))))
.........<<<<<<<...>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7utn Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9.
Resolution2.74 Å
Binding residue
(original residue number in PDB)
L14 M15 T17 R19 C20 R24 I25 K28 V34 V35 R37 F40 Y46 A49 E51 Q53 R86 M94 R97 Y100 R101 H104 R105 R106 R109 R110 K112 R113 R114 R115 R116 T122 F124 R131 P134 T141 K143 I145 R146 N147 K148 E149 A150 R151 F152 N153 N154 R155 K156 R157 P164 T165 H168 N175 F198 M199 R371 R372 H373 R375 Q376 A377 C378 R385 Y387 R398 H399 A401 M402 L409 R413 A418 S422 H428 M436 V446 Q483 L485 R486 N487
Binding residue
(residue number reindexed from 1)
L14 M15 T17 R19 C20 R24 I25 K28 V34 V35 R37 F40 Y46 A49 E51 Q53 R86 M94 R97 Y100 R101 H104 R105 R106 R109 R110 K112 R113 R114 R115 R116 T122 F124 R131 P134 T141 K143 I145 R146 N147 K148 E149 A150 R151 F152 N153 N154 R155 K156 R157 P164 T165 H168 N175 F198 M199 R274 R275 H276 R278 Q279 A280 C281 R288 Y290 R301 H302 A304 M305 L312 R316 A321 S325 H331 M339 V349 Q386 L388 R389 N390
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