Structure of PDB 7usq Chain D Binding Site BS01

Receptor Information
>7usq Chain D (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFM
HILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
Ligand information
Receptor-Ligand Complex Structure
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PDB7usq Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.
Resolution2.71 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 N208 S209 W214 S249 F250 F256
Binding residue
(residue number reindexed from 1)		Y21 S22 W23 R24 N25 S26 W31 S66 F67 F73
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7usq, PDBe:7usq, PDBj:7usq
PDBsum7usq
PubMed35642311
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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