Structure of PDB 7uso Chain D Binding Site BS01

Receptor Information
>7uso Chain D (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
Ligand information
Receptor-Ligand Complex Structure
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PDB7uso Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 S209 S249 F250 F256
Binding residue
(residue number reindexed from 1)		Y20 S21 W22 R23 S25 S65 F66 F72
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7uso, PDBe:7uso, PDBj:7uso
PDBsum7uso
PubMed35642311
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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