Structure of PDB 7ttr Chain D Binding Site BS01

Receptor Information
>7ttr Chain D (length=334) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKREAEERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLV
FLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGS
PPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRL
TDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMITISKNFKEN
VIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAKQ
RHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLL
PGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ttr Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Resolution2.96 Å
Binding residue
(original residue number in PDB)
G429 V431
Binding residue
(residue number reindexed from 1)
G103 V105
Enzymatic activity
Enzyme Commision number 3.6.1.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7ttr, PDBe:7ttr, PDBj:7ttr
PDBsum7ttr
PubMed36170828
UniProtQ9H078|CLPB_HUMAN Mitochondrial disaggregase (Gene Name=CLPB)

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