Structure of PDB 7to3 Chain D Binding Site BS01

Receptor Information
>7to3 Chain D (length=357) Species: 550 (Enterobacter cloacae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELQPQFNEFLANIRPTDTQKEDWKSGARTLRERLKNFEPLKEIVVSTFLQ
GSIRRSTAIRPLGDKRPDVDIVVVTNLDHTRMSPTDAMDLFIPFLEKYYP
GKWETQGRSFGITLSYVELDLVITAIPESGAEKSHLEQLYKSESVLTVNS
LEEQTDWRLNKSWTPNTGWLSSAQVEDAPASEWKAHPLVLPDREKNEWGR
THPLAQIRWTAEKNRLCNGHYINLVRAVKWWRQQNSEDLPKYPKGYPLEH
LIGNALDNGTTSMAQGLVQLMDTFLSRWAAIYNQKSKPWLSDHGVAEHDV
MARLTAEDFCSFYEGIASAAEIARNALASEEPQESAQLWRQLFGSKFPLP
QKTGRFA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7to3 Chain D Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7to3 An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
Resolution2.74 Å
Binding residue
(original residue number in PDB)		D69 D71
Binding residue
(residue number reindexed from 1)		D68 D70
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7to3, PDBe:7to3, PDBj:7to3
PDBsum7to3
PubMed36755092
UniProtP0DSP4|CDND2_ENTH5 Cyclic AMP-AMP-GMP synthase (Gene Name=cdnD02)

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