Structure of PDB 7t2d Chain D Binding Site BS01

Receptor Information
>7t2d Chain D (length=201) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQKVTQAQTEISVVEKEDVTLDCVYETRDTTYYLFWYKQPPSGELVFLIR
RNSFDEQNEISGRYSWNFQKSTSSFNFTITASQVVDSAVYFCALSGSARQ
LTFGSGTQLTVLPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQS
KDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTF
F
Ligand information
>7t2d Chain C (length=14) Species: 1313 (Streptococcus pneumoniae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ATGLAWEWWRTVYE
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7t2d CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
S112 R114
Binding residue
(residue number reindexed from 1)
S97 R99
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7t2d, PDBe:7t2d, PDBj:7t2d
PDBsum7t2d
PubMed37100059
UniProtP01848|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)

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