Structure of PDB 7t2c Chain D Binding Site BS01

Receptor Information
>7t2c Chain D (length=185) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGY
KTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGDTGFQKLVFG
TGTRLLVSPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSD
VYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANA
Ligand information
>7t2c Chain C (length=12) Species: 1313 (Streptococcus pneumoniae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TGLAWEWWRTVY
Receptor-Ligand Complex Structure
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PDB7t2c CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
T111 G112
Binding residue
(residue number reindexed from 1)
T92 G93
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7t2c, PDBe:7t2c, PDBj:7t2c
PDBsum7t2c
PubMed37100059
UniProtP01848|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)

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