Structure of PDB 7qrf Chain D Binding Site BS01

Receptor Information
>7qrf Chain D (length=80) Species: 11088 (Tick-borne encephalitis virus (WESTERN SUBTYPE)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATVRKERDGSTVIRAEGKDAATQVRVENGTCVILATDMGSWCDDSLSYEC
VTIDQGEEPVDVDCFCRNVDGVYLEYGRCG
Ligand information
>7qrf Chain C (length=5) Species: 11088 (Tick-borne encephalitis virus (WESTERN SUBTYPE)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7qrf Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.
Resolution2.28 Å
Binding residue
(original residue number in PDB)
A1 V3 V24 R25
Binding residue
(residue number reindexed from 1)
A1 V3 V24 R25
Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
External links
PDB RCSB:7qrf, PDBe:7qrf, PDBj:7qrf
PDBsum7qrf
PubMed35764616
UniProtP14336|POLG_TBEVW Genome polyprotein

[Back to BioLiP]