Structure of PDB 7qen Chain D Binding Site BS01

Receptor Information
>7qen Chain D (length=1050) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FSLSEYLTKFQTTDRESYPRLQDPSRELNVIIDQLAVSPEQIDASPDSLE
ALIDLCHDFPHLTPKLQTQLSYLISSSLSNLSKDIKANLSSNVNFTEIGG
LIPQWKRHLEEYGYLIQVLLTFLQDELHKVSSQSTNLNRSAKNSKNDSAN
VELFKRDCNQMENLLESITKLLEINLSKIFQTTPEKDLFIGLFTRPLFVL
LEIEPVTKVSSLKMFIQRILAMCVKNHGQSSSIQSSLMTNLTYFLHLSVF
NAELLKLLNDEYNYPQLTEDILKEISTRVFNAKDTTGPKAISNFLIKLSE
LSPGIMLRQMNLVITLLNNSSITLRCSVVEACGNIVAELAQDPQTMEHYK
QQIAVLIELLEERFQDSNPYVRTKAIQGCSKICDLSSKFNKSKAKFTSLA
VRSLQDRSSLVRRNSVKLLSKLLLKHPFKAIHGSQLRLSEWEEYLKGSES
QLNKLKLMIVYYKDAISFIKEIHKSIELISNLLFSKNRNEVLESMDFLVL
ADAFDIELSEFGIKKMLHLVWMKGTNDEGTSISVHLIECYKQLFLTAPDS
CNMQEKAAHIAKNLINLSIGASIADLASLEQLLGMMYEQKLIDQHVINIL
WAIYNSASKAGFSKEQIHGSIIILGMLSLADNEIALKGLESLLNIGLGAV
GLKDLTLCRYSCLALERMVPKRSTIAINQELEDVAVKKLYAIIINYTKDN
EYYPMCEQALSALFTISSKPDILATDLIREKTMMTFGKPQSSRVVSLSQL
LFIVGQVAIKTLVYLEKCEAEFKKRKIEAETRNGKTNEDDFTDAIQFVKE
NELLFGEKSILGKFCPIVEEIVSNSSRFSDPMLQRTATLCLEKLMCLSSK
YCEKSLPLLITVMEKSPDPTIRSNAVLGLGDMAVCFNNLVDENTDYLYRR
LHDENLMVQRTCLMTVTFLILAGQVKVKGQLGEMAKCLDNPDQGISDMCR
LFFTELASKDNAIYNGFIDIFSNLSSDDLLGKESFKKIIKFLLTFIDKER
HQKQLNEKLVGRLRKCETQKQWDDIAFVLNNLPYKNEDVTALLEQGFKVV
Ligand information
Receptor-Ligand Complex Structure
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PDB7qen A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Resolution3.46 Å
Binding residue
(original residue number in PDB)
R142 K292 Y373 K377 L413 G597 K1120 E1121
Binding residue
(residue number reindexed from 1)
R139 K289 Y370 K374 L410 G529 K998 E999
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0042393 histone binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0000278 mitotic cell cycle
GO:0007076 mitotic chromosome condensation
GO:0007130 synaptonemal complex assembly
GO:0010032 meiotic chromosome condensation
GO:0030261 chromosome condensation
GO:0030466 silent mating-type cassette heterochromatin formation
GO:0043007 maintenance of rDNA
GO:0044804 nucleophagy
GO:0051301 cell division
GO:0051307 meiotic chromosome separation
GO:0070058 tRNA gene clustering
GO:0070550 rDNA chromatin condensation
GO:1903342 negative regulation of meiotic DNA double-strand break formation
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0000796 condensin complex
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7qen, PDBe:7qen, PDBj:7qen
PDBsum7qen
PubMed35653469
UniProtQ06156|CND1_YEAST Condensin complex subunit 1 (Gene Name=YCS4)

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