Structure of PDB 7q2x Chain D Binding Site BS01

Receptor Information
>7q2x Chain D (length=994) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FSLSEYLTKFQTTDDPSRELNVIIDQLAVSPEQIPDSLEALIDLCHDFPH
LTPKLQTQLSYLISSSLSNLSKDIKANLGLIPQWKRHLEEYGYLIQVLLT
FLQDELHKVSSNVELFKRDCNQMENLLESITKLLEINLSKIFQTTPEKDL
FIGLFTRPLFVLLEIEPVTKVSSLKMFIQRILAMCVKNHGQSSSIQSSLM
TNLTYFLHLSVFNAELLKLLNDEYNYPQLTEDILKEISTRVFNAKDTTGP
KAISNFLIKLSELSPGIMLRQMNLVITLLNNSSITLRCSVVEACGNIVAE
LAQDPQTMEHYKQQIAVLIELLEERFQDSNPYVRTKAIQGCSKICDLSSK
FNKSKAKFTSLAVRSLQDRSSLVRRNSVKLLSKLLLKHPFKAIHGSQLRL
SEWEEYLKGSESQLNSTSVLMKLKLMIVYYKDAISFIKEIHKSIELISNL
LFSKNRNEVLESMDFLVLADAFDIELSEFGIKKMLHLVWMKSISVHLIEC
YKQLFLTAPDSCNMQEKAAHIAKNLINLSIGASIADLASLEQLLGMMYEQ
KLIDQHVINILWAIYNSASGFSKEQIHGSIIILGMLSLADNEIALKGLES
LLNIGLGAVGLKDLTLCRYSCLALERMVPKAINQELEDVAVKKLYAIIIN
YTKDNEYYPMCEQALSALFTISSKPDILATDLIREKTMMTFGKPSSRVVS
LSQLLFIVGQVAIKTLVYLEKCEAEFKKRKIEATNEDDFTDAIQFVKENE
LLFGEKSILGKFCPIVEEIVSNSSRFSDPMLQRTATLCLEKLMCLSSKYC
EKSLPLLITVMEKSPDPTIRSNAVLGLGDMAVCFNNLVDENTDYLYRRLH
DENLMVQRTCLMTVTFLILAGQVKVKGQLGEMAKCLDNPDQGISDMCRLF
FTELASKDNAIYNGFIDIFSNLSSDDLLGKESFKKIIKFLLTFIDKERHQ
KQLNEKLVGRLRKCETQKQWDDIAFVLNNLPYKNEDVTALLEQG
Ligand information
Receptor-Ligand Complex Structure
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PDB7q2x Clamping of DNA shuts the condensin neck gate.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Y373 L413 R416 E1121 R1122
Binding residue
(residue number reindexed from 1)		Y332 L372 R375 E947 R948
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0042393 histone binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0000278 mitotic cell cycle
GO:0007076 mitotic chromosome condensation
GO:0007130 synaptonemal complex assembly
GO:0010032 meiotic chromosome condensation
GO:0030261 chromosome condensation
GO:0030466 silent mating-type cassette heterochromatin formation
GO:0043007 maintenance of rDNA
GO:0044804 nucleophagy
GO:0051301 cell division
GO:0051307 meiotic chromosome separation
GO:0070058 tRNA gene clustering
GO:0070550 rDNA chromatin condensation
GO:1903342 negative regulation of meiotic DNA double-strand break formation
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0000796 condensin complex
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7q2x, PDBe:7q2x, PDBj:7q2x
PDBsum7q2x
PubMed35349345
UniProtQ06156|CND1_YEAST Condensin complex subunit 1 (Gene Name=YCS4)

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