Structure of PDB 7pnv Chain D Binding Site BS01

Receptor Information
>7pnv Chain D (length=343) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFFTKLTAEELWKGALAETGAGARKGRGKRTKKKKRKDLNRGQIIGEGRS
GFLWPGLNVPLIKSGVVQNIGQRSKEEQQKVEATMVEQREEWDRKRKIKV
KRERGWSGNTWGGVSIGPPDPGPNGETYEDFDTRILEVRNVFNMTAKEGR
KKSVRVLVAVGNGNGAAGFAIGKAADRGDAFRKAKNRAIHYLHYIERYEG
HTIFHDISLRFKRTQIRMKKQPRGYGLRCHRAIITICRLIGIKDMYARVT
GSMNMLNLTRGLFHGLARQETHQHLADKKGLHVVEFREECGPLPIVVASP
HGALSKEPEPEPEVPDTKLDWQDVKAMQGLKRSVWFNLKRPAT
Ligand information
>7pnv Chain A (length=951) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaagguuugguccuggccuuauaauuaauuagagguaaaauuacacaugc
aaaccuccauagaccgguguaaaaucccuuaaacauuuacuuaaaauuua
aggagaggguaucaagcacauuaaaauagcuuaagacaccuugccuagcc
acacccccacgggacucagcagugauaaauauuaagcaauaaacgaaagu
uugacuaaguuauaccucuuaggguugguaaauuucgugccagccaccgc
ggucauacgauuaacccaaacuaauuaucuucggcguaaaacgugucaac
uauaaauaaauaaauagaauuaaaauccaacuuauaugugaaaauucauu
guuaggaccuaaacucaauaacgaaaguaauucuagucauuuauaauaca
cgacagcuaagacccaaacugggauuagauaccccacuaugcuuagccau
aaaccuaaauaauuaauuaacaaaacuauuugccagagaacuacuagcca
uagcuuaaaacucaaaggacuuggcgguacuuuauauccaucuagaggag
ccuguucuauaaucgauaaaccccgcucuaccucaccaucucuugcuaau
ucagccuauauaccgccaucuucagcaaacccuaaaaagguauuaaagua
agcaaaagaaucaaacauaaaaacguuaggucaagguguagccaaugaaa
ugggaagaaaugggcuacauuuucuuauaaaagaacauuacuauacccuu
uaugaaacuaaaggacuaaggaggauuuaguaguaaauuaagaauagaga
gcuuaauugaauugagcaaugaaguacgcacacaccgcccgucacccucc
ucaaauuaaauuaaacuuaacauaauuaauuucuagacauccguuuauga
gaggagauaagucguaacaagguaagcauacuggaaagugugcuuggaau
a
..((((..<<<<<<.)))).<<<<<<<.<..<<<<<<<<..<.<<<.<<<
..<......>......<<......<<<<<<<<<..<<<<..>>>>.>>>>
>>>.>>.<<<....<<...<<....>>..>>......>>>..<<...>>.
>>.<<<....>>>.....>>>>>>>.........<<....<<<<....>>
>>..>>...>>.>>>>>>...<<<<<<<<.....(((.....((.>>>))
.......)))..>>>>>..>.>>>>>>>....<<<((.....<<<<....
<<............<<<<<<....<<<<<<<....<<......>>.....
>>>.>>>..>..........<<....>>.>>>>>>......>>....>>>
>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>...
.......<<<<.<<.....))..>>.>>>>.>>>.<<<.......<<<..
..>>>.....>>>..>>>>>><<<<<.<<<<<<........<<<<<..<<
<<<<<<<<.....<<........>>..........<<<<.<<........
...<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>>.
.>>......<<.....>>..........>>>...>>>>>>>>....>>.>
>>>..>>.>>>>>>>>.....<<<<<....>>>>>.....<<..<.<<<<
<<......>>>>>>..>.>>.....>>>>>.....<<<<<<<........
.>>>>>>>............>>>>>>>>>.>>....<..<<.<...<<<<
<<..<.<<<<<....<<....<<.....>>....>>......>>>>>>..
>>>>>>....>.>>...>.....<<<<<<<<<....>>>>>>>>>.....
.
Receptor-Ligand Complex Structure
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PDB7pnv Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Resolution3.06 Å
Binding residue
(original residue number in PDB)
T93 L95 L100 K102 G103 A106 T108 G109 G111 R116 K118 T120 K123 S196 G197 N198 R228 F231 N232 M233 A235 R244 K262 D268 R271 R276 R299 K301 R302 R317 C318 H319 R320 I323 Y335 A336 R337 S341 M342 N343 R349 W410 K420 S422 V423 W424 R429 T432
Binding residue
(residue number reindexed from 1)
T4 L6 L11 K13 G14 A17 T19 G20 G22 R27 K29 T31 K34 S107 G108 N109 R139 F142 N143 M144 A146 R155 K173 D179 R182 R187 R210 K212 R213 R228 C229 H230 R231 I234 Y246 A247 R248 S252 M253 N254 R260 W321 K331 S333 V334 W335 R340 T343
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7pnv, PDBe:7pnv, PDBj:7pnv
PDBsum7pnv
PubMed35676484
UniProtQ99N87|RT05_MOUSE Small ribosomal subunit protein uS5m (Gene Name=Mrps5)

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