Structure of PDB 7pnt Chain D Binding Site BS01

Receptor Information
>7pnt Chain D (length=337) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFFTKLTAEELWKGALAETGAGARKGKKKRKDLNRGQIIGEGRSGFLWPG
LNVPLIKSGVVQNIGQRSKEEQQKVEATMVEQREEWDRKRKIKVKRERGW
SGNTWGGVSIGPPDPGPNGETYEDFDTRILEVRNVFNMTAKEGRKKSVRV
LVAVGNGNGAAGFAIGKAADRGDAFRKAKNRAIHYLHYIERYEGHTIFHD
ISLRFKRTQIRMKKQPRGYGLRCHRAIITICRLIGIKDMYARVTGSMNML
NLTRGLFHGLARQETHQHLADKKGLHVVEFREECGPLPIVVASPHGALSK
EPEPEPEVPDTKLDWQDVKAMQGLKRSVWFNLKRPAT
Ligand information
>7pnt Chain A (length=909) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaagguuugguccuggccuuauaauuaauuagagguaaaauuacacaugc
aaaccuccauagaccgguguaaaaucccuuaaacauuuacuuaaaauuua
aggagaggguaucaagcacauuaaaauagcuuaagacaccuugccuagcc
acacccccacgggacucagcagugauaaauauuaagcaauaaacgaaagu
uugacuaaguuauaccucuuaggguugguaaauuucgugccagccaccgc
ggucauacgauuaacccaaacuaauuaucuucggcguaaaacgugucaac
uauaaauaaauaaauagaauuaaaauccaacuuauaugugaaaauucauu
guuaggaccuaaacucaauaacgaaaguaauucuagucauuuauaauaca
cgacagcuaagacccaaacugggauuagauaccccacuaugcuuagccau
aaaccuaaauaauuaaauuuaacaaaacuauuugccagagaacuacuagc
cauagcuuaaaacucaaaggacuuggcgguacuuuauauccaucuagagg
agccuguucuauaaucgauaaaccccgcucuaccucaccaucucuugcua
auucagccuauauaccgccaucuucagcaaacccuaaaaagguauuaaag
uaagcaaaagaaucaaacauaaaaacguuaggucaagguguagccaauga
aaugggaagaaaugggcuacauuuucuuauaaaagaacauuacuauaccc
uuuaugaaacuaaaggacuaaggaggauuuaguaguaaauuaagaauaga
gagcuuaauugaauugagcaaugaaguacgcacaccccuccuaaauuaaa
cuuaacauaauuaauuucuacguuuauggagauaaaagcauacugagugu
gcuuggaau
..((((..<<<<<<.)))).<<<<<<<.<..<<<<<<<<....<<<.<<<
..<......>......<<......<<<<<<<<<..<<<....>>>.>>>>
>>>.>>.<<<....<<...<<....>>..>>......>>>..<<...>>.
>>.<<<....>>>.....>>>>>>..........<<....<<<<....>>
>>..>>...>>.>>>>>>...<<<<<<<<.....(((.....((.>>>))
.......)))..>>>>>..>.>>>>>>>....<<<((.....<<<<....
<<............<<<<<<....<<<<<<<....<<......>>.....
>>>.>>>..>..........<<....>>.>>>>>>......>>....>>>
>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>...
.......<<<<.<<.......))..>>.>>>>.>>>.<<<.......<<<
....>>>.....>>>..>>>>>>.<<<<...<<<<........<<<<<..
<<<<<<<<<<.....<<........>>..........<<<<.<<......
.....<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>
>..>>......<<.....>>..........>>>...>>>>>>>>....>>
.>>>>..>>.>>>>>>>>.....<<<<<....>>>>>.....<<..<.<<
<<<<......>>>>>>..>.>>.....>>>>>.....<<<<<<<......
...>>>>>>>............>>>>..>>>.>....<<<<<<<<<....
......<<.....>>......>>>>>.>>>>....<<<<<<<<<.>>>>>
>>>>.....
Receptor-Ligand Complex Structure
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PDB7pnt Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Resolution3.19 Å
Binding residue
(original residue number in PDB)
T93 L95 L100 K102 G103 A106 T108 G109 G111 R113 K114 K122 K123 S196 G197 N198 R228 M233 K236 R239 R244 K262 R271 R276 R299 K301 R302 R317 C318 H319 R320 I323 Y335 A336 R337 S341 M342 R349 W410 K420 S422 V423 W424 R429
Binding residue
(residue number reindexed from 1)
T4 L6 L11 K13 G14 A17 T19 G20 G22 R24 K25 K27 K28 S101 G102 N103 R133 M138 K141 R144 R149 K167 R176 R181 R204 K206 R207 R222 C223 H224 R225 I228 Y240 A241 R242 S246 M247 R254 W315 K325 S327 V328 W329 R334
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7pnt, PDBe:7pnt, PDBj:7pnt
PDBsum7pnt
PubMed35676484
UniProtQ99N87|RT05_MOUSE Small ribosomal subunit protein uS5m (Gene Name=Mrps5)

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