Structure of PDB 7ow4 Chain D Binding Site BS01
Receptor Information
>7ow4 Chain D (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>7ow4 Chain F (length=8) Species:
9606
(Homo sapiens) [
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VVVGGVGK
Receptor-Ligand Complex Structure
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PDB
7ow4
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Resolution
1.81 Å
Binding residue
(original residue number in PDB)
Y7 Y9 E63 D77 Y84 Y99 D116 T143 W147 A150 Y159 R163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 E63 D77 Y84 Y99 D116 T143 W147 A150 Y159 R163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7ow4
,
PDBe:7ow4
,
PDBj:7ow4
PDBsum
7ow4
PubMed
UniProt
A0A583ZB34
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