Structure of PDB 7oqc Chain D Binding Site BS01

Receptor Information
>7oqc Chain D (length=576) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALRGLDTQFLQDNTALVQAYRGLDWSDISSLTQMVDVIEQTVVKYGNPND
SIKLALETILWQILRKYPLLFGFWKRFATIEYQLFGLKKSIAVLATSVKW
FPTSLELWCDYLNVLCVNNPNETDFIRNNFEIAKDLIGKQFLSHPFWDKF
IEFEVGQKNWHNVQRIYEYIIEVPLHQYARFFTSYKKFLNEKNLKTTRNI
DIVLRKTQTTVNEIWQFESKIKQPFFNLGQVLNDDLENWSRYLYHENTWM
MYIKWLTKKNISDEVVVDIYQKANTFLPLDFKTLRYDFLRFLKRKYRSNN
TLFNNIFNETVSRYLKIWPNDILLMTEYLCMLKRHSFKNSLDQSPKEILE
KQTSFTKILETSITNYINNQIDAKVHLQTLINDKNLSIVVVELIKTTWLV
LKNNMQTRKYFNLYQKNILIKNSVPFWLTYYKFEKSNVNFTKLNKFIREL
GVEIYLPTTVMNDILTDYKTFYLTHSNIVTYESSIIDSNTFDPILYPELK
MSNPKYDPVDWHKKTEWKEAGHIGITTERPQISNSIIECNSGTLIQKPIS
LPNFRNLEKINQVKINDLYTEEFLKE
Ligand information
>7oqc Chain I (length=63) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB7oqc Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		F605 R606 N607 E609
Binding residue
(residue number reindexed from 1)		F554 R555 N556 E558
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030627 pre-mRNA 5'-splice site binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0071004 U2-type prespliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7oqc, PDBe:7oqc, PDBj:7oqc
PDBsum7oqc
PubMed34349264
UniProtP39682|PRP39_YEAST Pre-mRNA-processing factor 39 (Gene Name=PRP39)

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